Advancing Cancer Research Through Collaboration
Friends of Cancer Research (Friends) is working to accelerate policy change, support groundbreaking science, and deliver new therapies to patients quickly and safely.
About Friends
2022 Scientific Report
Our 2022 Scientific Report contains the full text of our 2022 white papers and publications to serve as a resource for those in the drug development and regulatory space.
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2022 Impact Report: Patient-Centered Innovation
Our 2022 Impact Report is a snapshot of our exciting research and policy programs from the past year. We are proud to work alongside leaders in our field to advance cancer research and treatment.
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Who We Are,
What We Drive

Friends of Cancer Research drives collaboration among partners from every healthcare sector to power advances in science, policy, and regulation that speed life-saving treatments to patients.

Circulating Tumor DNA (ctDNA)
ctDNA to Monitor Treatment Response (ctMoniTR) is a first of its kind partnership led by Friends of Cancer Research (Friends) to answer the question: Do changes in ctDNA reflect response to treatment?
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Real-World Evidence
The Friends of Cancer Research Real-World Evidence portfolio develops and establishes methodology for using Real-World Data to demonstrate benefit to patients.
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Homologous Recombination Deficiency (HRD)
The Homologous Recombination Deficiency (HRD) Harmonization Project supports the future use of assays that measure the HRD biomarker for treatment decision making. Friends is currently examining sources of variability across HRD tests and identifying opportunities for alignment while proposing solutions to improve agreement in the future.
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Homologous Recombination Deficiency (HRD)
The Homologous Recombination Deficiency (HRD) Harmonization Project supports the future use of assays that measure the HRD biomarker for treatment decision making. Friends is currently examining sources of variability across HRD tests and identifying opportunities for alignment while proposing solutions to improve agreement in the future.
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Tumor Mutational Burden (TMB)
The Tumor Mutational Burden (TMB) Harmonization Project was completed in 2021 and supports the use of assays that measure TMB for treatment decision making by examining sources of variability across assays and identifying opportunities for alignment.
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Supporting the Development of Diagnostic Tests
On Tuesday, February 22, 2022, Friends of Cancer Research hosted a live virtual event that brought together leading voices from various health sectors to discuss key considerations for developing diagnostics tests for rare populations of patients, including those with rare diseases and rare biomarkers.
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Data Driven Insights Dashboards
Friends has created a series of interactive dashboards as a tool to gain data driven insights into the landscape of oncology drug development and FDA drug approvals.
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Breakthrough
Working with our partners in all sectors, Friends took ‘Breakthrough’ from concept, to scientific whitepaper, to bipartisan legislative solution, to a tool in full use by FDA to expedite the approval of multiple drugs in 13 months. On November 1, 2013, only a year after being signed into law and 29 designations had been announced, the first Breakthrough designation received full FDA approval.
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ProgressForPatients.org
ProgressforPatients.org brings together patients and their advocates as we work to incorporate the patient voice into research and drug development. We strive to then connect advocates with opportunities taking place at institutions and organizations across the regulatory landscape from government agencies, advocacy groups, industry partners, and more.
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Eligibility Criteria
Eligibility criteria are necessary in clinical trials to define the patient population, isolate the potential effect of an investigational drug, and ensure that the trial is conducted safely. However, overly strict eligibility criteria may impair the rate of trial accrual, restrict patient access to investigational drugs, and limit the ability to generalize the results to the broader population of patients who will ultimately use the drug.
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Clinical Trials
What is a clinical trial? How does it impact patients? Click here to learn more about this important piece in the drug development process.
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Our Power of Collaboration

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